Dosing and Dose Equivalence of Metformin |
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Initial dose | Titration | Maximum dose | |
Metformin (Glucophage) IR Tab |
500 mg BID |
500 mg Qweek |
2550mg/day in 2 or 3 doses |
Metformin (Glucophage) XR Tab |
850 mg QDay |
850 mg Qweek |
2550mg/day in 2 or 3 doses |
Metformin (Riomet) IR solution (100mg/mL) |
500 mg BID OR 850 mg QDay |
500 mg QWeek OR 850 mg Q2weeks OR From 500mg BID to 850mg BID after 2weeks |
2550mg/day in three divided doses.
|
Metformin (Fortamet) XR TAB |
500 mg QDay OR 1000 mg QDay |
500 mg QWeek
|
2500mg/day |
Metformin (Glumetza) XR |
500 mg QDay |
500 mg Qweek or Q2weeks |
2000 mg/day |
Metformin Generic (Avkare) XR Tab |
500 mg QDay |
500 mg Qweek |
2000 mg/day |
Metformin Generic (Amneal) XR Tab |
500 mg QDay |
500 mg Qweek |
2000 mg/day |
Last updated: 04/22/13 By: Christian Mbangha Muenyi
References:
Metformin. In: DRUGDEX (Internet Database). Ann Arbor, MI, Thomson Reuters (Healthcare) Inc.
Metformin Hydrochloride Extended release Tablets (Avkare) package insert. Pulaski, TN 38478.
Metformin Hydrochloride Extended release Tablets (Amneal) package insert. Glasgow, KY 42141.