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Growth hormone’s release is pulsatile. There are spikes of GH release with an overall low concentration in the body. Therefore, its measurement is meaningless. GH targets fat and liver cells to produce IGF-1. Insulin induced hypoglycemia stimulates GH release and hyperglycemia inhibits GH release. GH action occurs when it binds to its membrane receptor. Membrane […]

Factrel Half life is 2 to 4 minutes; used for diagnostic purposes to differentiate between pituitary and hypothalamic defects in patients with hypogonadotropic hypogonadism. Lutrepulse Half life is 2 to 4 minutes; used to treat patients with reproductive disorders secondary to deficiency of GnRH or disordered secretion of GnRH. It is administered via IV with […]

Endometriosis is a condition in which the tissue that normally lines the uterus (endometrium) grows in other areas of the body, causing pain, irregular bleeding, and possible infertility. The tissue growth (implant) typically occurs in the pelvic area, outside of the uterus, on the ovaries, bowel, rectum, bladder, and the delicate lining of the pelvis. […]

When diagnosed and treated early, prognosis is good. Medical and surgical treatments can relieve 90% of the pain of endometriosis in women. However the recurring rate for all types of conservative surgery is 20% within 5 years. Even without treatment, 3 out of 4 women with mild endometriosis can still become pregnant. Of those women […]

Virtually all vertebrates have an Oxytocin like nonapeptide hormone that supports reproductive functions in a vasopressin-like nonapeptide hormone involved in water regulation. The two genes are always located close to each other (less than fifteen thousand DNA bases apart on the same chromosome and are transcribed in opposite directions). It is thought that two genes […]

DESCRIPTION A peptide is defined as low molecular weight polymers of less than 40 amino acids joined together by amide linkages. Oxytocin, often abbreviated OXT, is included in this group and is a nonapeptide, meaning that it contains a sequence of nine peptides. The sequence is cysteine, tyrosine, isoleucine, glutamine, asparagine, cysteine, proline, leucine, and […]

Ever wondered which releasing factors stimulate the secretion of which respective hormone in the pituitary gland? Or what inhibits the secretion of hormones in the pituitary gland? This clinical chart provides the answer. Stimulators Via Positive Regulation Thyroid Releasing Hormone (TRH ) Thyroid Stimulating Hormone and Prolactin (TSH and PRl) GNRH (Gonadotropin Releasing Hormone) FSH […]

“Feel your boobies.” I remember first seeing a breast cancer awareness car magnet while finishing my P3 year of pharmacy school in Winchester, VA. Admittedly direct, the magnet certainly piqued my curiosity for and awareness of breast cancer. Shortly after observing that magnet about raising breast cancer awareness, I received an e-mail for a breast […]

Endocrine Glands Include Pituitary Pineal Thyroid Thymus Pancreas Ovary Adrenal * 2 Parathyroid * 4 Testes * 2  Adenohypophysis = anterior pituitary Its hormones are essential for: Regulating growth and development Stimulating the reproductive system Providing a response to stress Regulating intermediary metabolism Synthesis and secretion of adenohypophysis hormones are controlled by: Hypothalamic factors Peripheral […]