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Cystic Fibrosis: An Overview

Vision impaired? Listen to this article! Cystic Fibrosis (CF) is an autosomal recessive disease and the most common lethal genetic disease in Caucasians. It occurs as a result of a mutation in CF gene, which is found in chromosome 7. The CF gene regulates the production of the cystic fibrosis transmembrane regulator protein (CFTR) protein […]

Pediatric Kinetics: Pharmacologic Considerations in Newborns

Vision impaired? Listen to this article! Last Updated: April 2, 2013 Gone are the days when children were considered to be “little adults”. Thanks to the advent of cytochrome P450 (CYP) enzymes and detailed knowledge of pediatric metabolism, we now know that absorption, distribution, metabolism, and excretion (ADME) functions of adults differs highly from that […]